Antidepressant sertraline increases thioflavin-S and Congo red deposition in APPswe/PSEN1dE9 transgenic mice

Introduction: Depression is strongly associated with Alzheimer’s disease (AD). Antidepressants are commonly used in patients before and after their diagnosis of AD. To date, the relationship between antidepressants and AD remains unclear.Methods: In our study, we administered sertraline or paroxetin...

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Hauptverfasser:	Ming-Hsuan Liao, Yen-Kuang Lin, Fong-Ying Gau, Chun-Che Tseng, Da-Chih Wu, Chu-Yuan Hsu, Kuo-Hsuan Chung, Rung-Chi Li, Chaur-Jong Hu, Chee Kin Then, Shing-Chuan Shen
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2024-01-01
Schriftenreihe:	Frontiers in Pharmacology
Schlagworte:	sertraline paroxetine SSRI β-amyloid Alzheimer’s disease APP/PSEN1
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fphar.2023.1260838/full
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