AIE-active dual-channel fluorescent probe for simultaneous viscosity and HClO detection in ferroptosis, acute liver injury and hepatocellular carcinoma models

This study addresses the technical challenge of simultaneously detecting viscosity and hypochlorous acid (HClO) within the liver disease microenvironment by developing a novel near-infrared (NIR) dual-channel fluorescence probe, BCz-DCN-TPA, based on the aggregation-induced emission (AIE) mechanism....

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Autors principals:	Jiakang Sun, Lidong Cao, Yumeng Liu, Yun Wang, Yong Zhan
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2026-04-01
Col·lecció:	Journal of Pharmaceutical Analysis
Matèries:	Fluorescent probe Near-infrared imaging Aggregation-induced emission Dual-channel response Viscosity and HClO detection Photoacoustic imaging
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S2095177925003065
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