Comparison of intra-articular injectable polydactyly-derived chondrocyte sheet-minis with direct transplantation of intact polydactyly-derived chondrocyte sheets in a rat full-thickness cartilage defect model

Introduction: Polydactyly-derived chondrocyte (PD) sheets are being developed as an allogeneic cell sheet therapy for cartilage defects associated with knee osteoarthritis. Although intact PD sheets can promote hyaline cartilage repair, transplantation requires invasive open procedures. Injectable f...

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Bibliografische Detailangaben

Hauptverfasser:	Makoto Ogawa, Eriko Toyoda, Shiho Wasai, Tatsumi Tanaka, Ryoka Uchiyama, Miki Maehara, Tadashi Akamatsu, Masahiko Watanabe, Masato Sato
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2026-12-01
Schriftenreihe:	Regenerative Therapy
Schlagworte:	Polydactyly-derived chondrocyte Cell sheet Sheet-mini Cartilage repair Osteoarthritis Xenogeneic transplantation
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S2352320426000933
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