Intratumor microbiome-derived butyrate enhances progesterone sensitivity by inducing ferroptosis in endometrial cancer

Endometrial cancer (EC) is increasingly affecting younger women, and progesterone therapy remains the cornerstone of fertility-preserving treatment (FPT). However, progesterone resistance presents a major clinical challenge. While the tumor microbiome and its metabolites have been implicated in vari...

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Detalhes bibliográficos

Principais autores:	Xingchen Li, Yiqin Wang, Yuman Wu, Jingyuan Wang, Yue Qi, Xinyi Bi, Jianliu Wang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2025-09-01
Colecção:	Pharmacological Research
Assuntos:	Endometrial cancer Intratumor microbiome Butyrate Ferroptosis Progesterone resistant
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S1043661825003275
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