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Dual roles for ATP in the regulation of phase separated protein aggregates in Xenopus oocyte nucleoli

For many proteins, aggregation is one part of a structural equilibrium that can occur. Balancing productive aggregation versus pathogenic aggregation that leads to toxicity is critical and known to involve adenosine triphosphate (ATP) dependent action of chaperones and disaggregases. Recently a seco...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Michael H Hayes, Elizabeth H Peuchen, Norman J Dovichi, Daniel L Weeks
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications Ltd 2018-07-01
Schriftenreihe:eLife
Schlagworte:
protein aggregation
nucleolus
nucleus
oocyte
ATP
Online-Zugang:https://elifesciences.org/articles/35224
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