Impact of mesoporous silica on the chemical degradation of Praziquantel upon grinding

Praziquantel and Syloid 244 FP (amorphous silicon dioxide) were ground in a vibrational mill in standard conditions ($15^{\prime}$ or $30^{\prime}$ at 25 Hz). Amorphous solid dispersions were obtained in a very short grinding time (15 min), as testified by DSC, PXRD and ESEM analyses. Samples ground...

Disgrifiad llawn

Manylion Llyfryddiaeth

Prif Awduron:	Šagud, Ivana, Zanolla, Debora, Zingone, Guglielmo, Perissutti, Beatrice, Škorić, Irena
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Académie des sciences 2021-05-01
Cyfres:	Comptes Rendus. Chimie
Pynciau:	Degradation products Grinding Mesoporous silica Oxidation Praziquantel Ring opening
Mynediad Ar-lein:	https://comptes-rendus.academie-sciences.fr/chimie/articles/10.5802/crchim.82/
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