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Chuanxiong Rhizoma regulates ferroptosis and the immune microenvironment in ischemic stroke through the JAK-STAT3 pathway

Abstract Ferroptosis is linked to various pathological conditions; however, the specific targets and mechanisms through which traditional Chinese medicine influences ischemic stroke (IS)-induced ferroptosis remain poorly understood. In this study, data from the Gene Expression Omnibus and disease ta...

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Principais autores: Qianxi Ge, Zhimin Wang, Jiaxiang Yu, Xiuzhi Feng, Jiquan Li, Xiaoqing Zhang, Shaohong Wang, Lie Wang, Yiran Chen
Format: Artigo
Sprog:Inglês
Udgivet: Nature Portfolio 2024-12-01
Serier:Scientific Reports
Fag:
Ischemic stroke
Chuanxiong Rhizoma
Ferroptosis
Immune microenvironment
Online adgang:https://doi.org/10.1038/s41598-024-82486-5
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