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Antiplasmodial and Cytotoxic Activities of Drimane Sesquiterpenes from

The hexane extract from the leaves of Canella winterana exhibited strong activity against the chloroquine sensitive (CQS) strain of Plasmodium falciparum (D10) in vitro (IC 50 2.53 μg/mL). Bioassay guided fractionation of this extract has led to the isolation of 5 drimane-type sesquiterpenoids: 9-ep...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Mary H. Grace, Carmen Lategan, Flaubert Mbeunkui, Rocky Graziose, Peter J. Smith, Ilya Raskin, Mary Ann Lila
Format: Artigo
Sprache:Inglês
Veröffentlicht: SAGE Publishing 2010-12-01
Schriftenreihe:Natural Product Communications
Online-Zugang:https://doi.org/10.1177/1934578X1000501205
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