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Single cell RNA seq reveals the pro-regenerative phenotype of thrombospondin-2 deficient dermal fibroblasts

Abstract Fibroblasts display complex functions linked to distinct gene expression profiles. These profiles influence matrix production, cell communication, and tissue development and repair. Thrombospondin-2 (TSP2), produced by fibroblasts, is a potent angiogenesis inhibitor and negatively associate...

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Bibliografiske detaljer
Principais autores: Yaqing Huang, Nuoya Wang, Hao Xing, Daqian Gao, Henry C. Hsia, Micha Sam Brickman Raredon, Themis R. Kyriakides
Format: Artigo
Sprog:Inglês
Udgivet: Nature Portfolio 2025-09-01
Serier:Scientific Reports
Fag:
Online adgang:https://doi.org/10.1038/s41598-025-15839-3
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