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Neuregulin-4 protects cardiomyocytes against high-glucose-induced ferroptosis via the AMPK/NRF2 signalling pathway

Abstract Background High glucose levels are key factors and key contributors to several cardiovascular diseases associated with cardiomyocyte injury. Ferroptosis, which was identified in recent years, is a mode of cell death caused by the iron-mediated accumulation of lipid peroxides. Neuregulin-4 (...

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Principais autores: Pengfei Wang, Xiaohua Guo, Hongchao Wang, Lijie Wang, Meifang Ma, Bingyan Guo
פורמט: Artigo
שפה:Inglês
יצא לאור: BMC 2024-08-01
סדרה:Biology Direct
נושאים:
Neuregulin-4
Diabetic cardiomyopathy
Ferroptosis
AMPK
NRF2
גישה מקוונת:https://doi.org/10.1186/s13062-024-00505-x
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