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The Challenges and Strategies of Antisense Oligonucleotide Drug Delivery

Antisense oligonucleotides (ASOs) are used to selectively inhibit the translation of disease-associated genes via Ribonuclease H (RNaseH)-mediated cleavage or steric hindrance. They are being developed as a novel and promising class of drugs targeting a wide range of diseases. Despite the great pote...

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Autori principali: Maria Gagliardi, Ana Tari Ashizawa
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2021-04-01
Serie:Biomedicines
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Accesso online:https://www.mdpi.com/2227-9059/9/4/433
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