Tag-based next generation sequencing: a feasible and reliable assay for EGFR T790M mutation detection in circulating tumor DNA of non small cell lung cancer patients

Abstract Background The demonstration of EGFR T790M gene mutation in plasma is crucial to assess the eligibility of Non Small Cell Lung Cancer (NSCLC) patients, who have acquired resistance to first or second generation Tyrosine Kinase Inhibitors (TKIs), to receive a subsequent treatment with osimer...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Mariella Dono, Giuseppa De Luca, Sonia Lastraioli, Giorgia Anselmi, Maria Giovanna Dal Bello, Simona Coco, Irene Vanni, Francesco Grossi, Antonella Vigani, Carlo Genova, Manlio Ferrarini, Jean Louis Ravetti, Simona Zupo
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	BMC 2019-04-01
Цуврал:	Molecular Medicine
Нөхцлүүд:	Circulating tumor DNA Liquid biopsy NSCLC EGFR TKIs T790M resistance mutation Molecular tag
Онлайн хандалт:	http://link.springer.com/article/10.1186/s10020-019-0082-5
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!