In vitro co-culture studies and the crucial role of fibroblast-immune cell crosstalk in IPF pathogenesis

Abstract IPF is a fatal lung disease characterized by intensive remodeling of lung tissue leading to respiratory failure. The remodeling in IPF lungs is largely characterized by uncontrolled fibrosis. Fibroblasts and their contractile phenotype the myofibroblast are the main cell types responsible f...

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Detalhes bibliográficos

Principais autores:	Fama Thiam, Sakshi Phogat, Filsan Ahmed Abokor, Emmanuel Twumasi Osei
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2023-11-01
coleção:	Respiratory Research
Assuntos:	Pulmonary fibroblasts Pulmonary immune cells Idiopathic pulmonary fibrosis Multicellular crosstalk Co-culture models Extracellular matrix
Acesso em linha:	https://doi.org/10.1186/s12931-023-02608-x
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