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A zinc finger transcription factor enables social behaviors while controlling transposable elements and immune response in prefrontal cortex

Abstract The neurobiological origins of social behaviors are incompletely understood. Here we utilized synthetic biology approaches to reprogram the function of ZFP189, a transcription factor whose expression and function in rodent prefrontal cortex was previously demonstrated to be protective again...

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Autori principali: Natalie L. Truby, R. Kijoon Kim, Gabriella M. Silva, Xufeng Qu, Joseph A. Picone, Rebecca Alemu, Claire N. Atiyeh, Rachael L. Neve, Jinze Liu, Xiaohong Cui, Peter J. Hamilton
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2024-01-01
Serie:Translational Psychiatry
Accesso online:https://doi.org/10.1038/s41398-024-02775-5
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