Uracil restores susceptibility of methicillin-resistant Staphylococcus aureus to aminoglycosides through metabolic reprogramming

Background: Methicillin-resistant Staphylococcus aureus (MRSA) has now become a major nosocomial pathogen bacteria and resistant to many antibiotics. Therefore, Development of novel approaches to combat the disease is especially important. The present study aimed to provide a novel approach involvin...

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Principais autores:	Lvyuan Fan, Zhiyu Pan, Xu Liao, Yilin Zhong, Juan Guo, Rui Pang, Xinhai Chen, Guozhu Ye, Yubin Su
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2023-01-01
coleção:	Frontiers in Pharmacology
Assuntos:	methicillin-resistant Staphylococcus aureus uracil gentamicin TCA cycle ROS metabolic reprogramming
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fphar.2023.1133685/full
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