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Structural elucidation of substrate-bound aminoglycoside acetyltransferase (3)-IIIa.

Canonical aminoglycosides are a large group of antibiotics, where the part of chemical diversity stems from the substitution of the neamine ring system on positions 5 and 6. Certain aminoglycoside modifying enzymes can modify a broad range of 4,5- and 4,6-disubstituted aminoglycosides, with some as...

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Auteurs principaux: Michał Zieliński, Jonathan Blanchet, Sophia Hailemariam, Albert M Berghuis
Format: Artigo
Langue:Inglês
Publié: Public Library of Science (PLoS) 2022-01-01
Collection:PLoS ONE
Accès en ligne:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0269684&type=printable
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