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From microelectrode arrays to all-optical and multimodal neural interfaces: emerging platforms for spatiotemporal interrogation of in vitro neural circuits

Understanding how synaptic interactions lead to circuit dynamics for neural computation requires experimental tools that can both observe and perturb neuronal activity across spatial and temporal scales. Microelectrode arrays (MEAs) provide scalable access to population spiking activity, yet they la...

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Principais autores: Song Wang, Sarah Gordon, Chris French, Ranjith R. Unnithan, Dechuan Sun
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2025-12-01
Serier:Frontiers in Synaptic Neuroscience
Fag:
microelectrode array
all-optical interrogation
patterned photostimulation
multimodal neural interfaces
synaptic plasticity
network dynamics
Online adgang:https://www.frontiersin.org/articles/10.3389/fnsyn.2025.1732955/full
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