Increased runs of homozygosity in the autosomal genome of Brazilian individuals with neurodevelopmental delay/intellectual disability and/or multiple congenital anomalies investigated by chromosomal microarray analysis

Abstract Runs of homozygosity (ROH) in the human genome may be clinically relevant. The aim of this study was to report the frequency of increased ROH of the autosomal genome in individuals with neurodevelopmental delay/intellectual disability and/or multiple congenital anomalies, and to compare the...

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Main Authors:	Gabriela Roldão Correia-Costa, Ilária Cristina Sgardioli, Ana Paula dos Santos, Tânia Kawasaki de Araujo, Rodrigo Secolin, Iscia Lopes-Cendes, Vera Lúcia Gil-da-Silva-Lopes, Társis Paiva Vieira
Format:	Artigo
Language:	Inglês
Published:	Sociedade Brasileira de Genética 2022-02-01
Series:	Genetics and Molecular Biology
Subjects:	Runs of homozygosity chromosomal microarray analysis identity by descent uniparental disomy
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572022000100107&lng=en&tlng=en
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