Determining the functional relationship between epigenetic and physical chromatin domains in Drosophila

Abstract The tight correlation between topologically associating domains (TADs) and epigenetic domains in Drosophila suggests that the epigenome contributes to define TADs. However, it is still unknown whether histone modifications are essential for TAD formation and structure. By either deleting or...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Sandrine Denaud, Gonzalo Sabarís, Marco Di Stefano, Giorgio-Lucio Papadopoulos, Bernd Schuettengruber, Giacomo Cavalli
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	BMC 2025-05-01
Цуврал:	Genome Biology
Нөхцлүүд:	Chromatin Genome organization Epigenome TADs Drosophila PcG proteins
Онлайн хандалт:	https://doi.org/10.1186/s13059-025-03587-6
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!