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Oxidative stress induces cell death partially by decreasing both mRNA and protein levels of nicotinamide phosphoribosyltransferase in differentiated PC12 cells

Background. Multiple studies have indicated crucial roles of NAD+ deficiency in several neurological diseases and aging. It is critical to discover the mechanisms underlying the NAD+ deficiency. A decreased level of Nicotinamide phosphoribosyltransferase (Nampt)—an important enzyme in the salvage pa...

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Bibliografske podrobnosti
Principais autores: Cuiyan Zhou, Weihai Ying
Format: Artigo
Jezik:Inglês
Izdano: PeerJ Inc. 2021-05-01
Serija:PeerJ
Teme:
Online dostop:https://peerj.com/articles/11401.pdf
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