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Zebrafish tsc1 and cxcl12a increase susceptibility to mycobacterial infection

Knockdown of miR-126 increases susceptibility to mycobacterial infection which can be independently reversed by targeting Tsc1/mTOR or ccr2 implicating macrophage function. Regulation of host miRNA expression is a contested node that controls the host immune response to mycobacterial infection. The...

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Hlavní autoři: Kathryn Wright, Darryl JY Han, Renhua Song, Kumudika de Silva, Karren M Plain, Auriol C Purdie, Ava Shepherd, Maegan Chin, Elinor Hortle, Justin J-L Wong, Warwick J Britton, Stefan H Oehlers
Médium: Artigo
Jazyk:Inglês
Vydáno: Life Science Alliance LLC 2024-04-01
Edice:Life Science Alliance
On-line přístup:https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.202302523
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