Vascular and pulmonary effects of ibuprofen on neonatal lung development

Abstract Background Ibuprofen is a nonsteroidal anti-inflammatory drug that is commonly used to stimulate closure of a patent ductus arteriosus (PDA) in very premature infants and may lead to aberrant neonatal lung development and bronchopulmonary dysplasia (BPD). Methods We investigated the effect...

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Autors principals:	Xueyu Chen, Dongshan Han, Xuan Wang, Xuemei Huang, Zilu Huang, Yijun Liu, Junyan Zhong, Frans J. Walther, Chuanzhong Yang, Gerry T. M. Wagenaar
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2023-02-01
Col·lecció:	Respiratory Research
Matèries:	Bronchopulmonary dysplasia Lung inflammation Alveolarization Pulmonary arterial hypertension Angiogenesis Cell cycle arrest
Accés en línia:	https://doi.org/10.1186/s12931-023-02342-4
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