Molecular Characterisation of Small Molecule Agonists Effect on the Human Glucagon Like Peptide-1 Receptor Internalisation.

The glucagon-like peptide receptor (GLP-1R), which is a G-protein coupled receptor (GPCR), signals through both Gαs and Gαq coupled pathways and ERK phosphorylation to stimulate insulin secretion. The aim of this study was to determine molecular details of the effect of small molecule agonists, comp...

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Detalhes bibliográficos

Principais autores:	Aiysha Thompson, Jeffrey W Stephens, Stephen C Bain, Venkateswarlu Kanamarlapudi
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2016-01-01
coleção:	PLoS ONE
Acesso em linha:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0154229&type=printable
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