Poly(N-isopropylacrylamide-co-N-vinylpyrrolidone) thermoresponsive microspheres: The low drug loading ensures the pulsatile release mechanism

Poly(N-isopropylacrylamide-co-N-vinylpyrrolidone) (poly(NIPAAm-co-NVP)) with a co-monomer molar ratio in copolymer of 91.5/8.5 (NIPAAm/NVP) was synthesized as an interesting thermosensitive material possessing a sharp phase transition at 36 °C under simulated physiological conditions. The effect of...

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Hlavní autoři: G. Fundueanu, M. Constantin, S. Bucatariu, P. Ascenzi
Médium: Artigo
Jazyk:Inglês
Vydáno: Budapest University of Technology and Economics 2020-01-01
Edice:eXPRESS Polymer Letters
Témata:
smart polymers
poly(n-isopropylacrylamide)
drug delivery
microspheres
stimuli-sensitive polymers
On-line přístup:http://www.expresspolymlett.com/letolt.php?file=EPL-0010125&mi=cd
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