Measurement of circulating CD21−CD27− B lymphocytes in SLE patients is associated with disease activity independently of conventional serological biomarkers

Abstract Determining disease activity in systemic lupus erythematosus (SLE) patients is challenging and limited by the lack of reliable biomarkers. Abnormally activated B cells play a key role in the pathogenesis of SLE, but their measure in clinical practice is currently not recommended. Here, we s...

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Ngā kaituhi matua:	Alice Horisberger, Morgane Humbel, Natalia Fluder, Florence Bellanger, Craig Fenwick, Camillo Ribi, Denis Comte
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	Nature Portfolio 2022-06-01
Rangatū:	Scientific Reports
Urunga tuihono:	https://doi.org/10.1038/s41598-022-12775-4
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!