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Permeability of the Retina and RPE-Choroid-Sclera to Three Ophthalmic Drugs and the Associated Factors

In this study, Retina-RPE-Choroid-Sclera (RCS) and RPE-Choroid-Sclera (CS) were prepared by scraping them off neural retina, and using the Ussing chamber we measured the average time–concentration values in the acceptor chamber across five isolated rabbit tissues for each drug molecule. We determine...

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Principais autores: Hyeong Min Kim, Hyounkoo Han, Hye Kyoung Hong, Ji Hyun Park, Kyu Hyung Park, Hyuncheol Kim, Se Joon Woo
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2021-05-01
Serier:Pharmaceutics
Fag:
permeability
retina
retinal pigment epithelium
Ussing chamber
intravitreal half-life
Online adgang:https://www.mdpi.com/1999-4923/13/5/655
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