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Targeting Mitochondrial Metabolism and RNA Polymerase POLRMT to Overcome Multidrug Resistance in Cancer

Clinically, the prognosis of tumor therapy is fundamentally affected by multidrug resistance (MDR), which is primarily a result of enhanced drug efflux mediated by channels in the membrane that reduce drug accumulation in tumor cells. How to restore the sensitivity of tumor cells to chemotherapy is...

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Bibliografische gegevens
Hoofdauteurs: Hui-Jing Yu, Guan-Li Xiao, Yu-Ying Zhao, Xin-Xin Wang, Rongfeng Lan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2021-12-01
Reeks:Frontiers in Chemistry
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Online toegang:https://www.frontiersin.org/articles/10.3389/fchem.2021.775226/full
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