Substantially thinner internal granular layer and reduced molecular layer surface in the cerebellar cortex of the Tc1 mouse model of down syndrome – a comprehensive morphometric analysis with active staining contrast-enhanced MRI

Down Syndrome is a chromosomal disorder that affects the development of cerebellar cortical lobules. Impaired neurogenesis in the cerebellum varies among different types of neuronal cells and neuronal layers. In this study, we developed an imaging analysis framework that utilizes gadolinium-enhanced...

وصف كامل

التفاصيل البيبلوغرافية

المؤلفون الرئيسيون:	Da Ma, Manuel J. Cardoso, Maria A. Zuluaga, Marc Modat, Nick M. Powell, Frances K. Wiseman, Jon O. Cleary, Benjamin Sinclair, Ian F. Harrison, Bernard Siow, Karteek Popuri, Sieun Lee, Joanne A. Matsubara, Marinko V. Sarunic, Mirza Faisal Beg, Victor L.J. Tybulewicz, Elizabeth M.C. Fisher, Mark F. Lythgoe, Sebastien Ourselin
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	Elsevier 2020-12-01
سلاسل:	NeuroImage
الموضوعات:	Cerebellar cortical laminar structure Down syndrome Cortical volume Cortical thickness Cortical surface area Active staining
الوصول للمادة أونلاين:	http://www.sciencedirect.com/science/article/pii/S1053811920307576
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!