Identification of a putative progenitor-like chondrocyte subpopulation in osteoarthritic human cartilage

Abstract Background Osteoarthritis (OA) is a degenerative joint disease characterized by progressive cartilage breakdown and limited intrinsic repair capacity. Recent single-cell RNA sequencing (scRNA-seq) studies have revealed remarkable chondrocyte heterogeneity, identifying multiple functionally...

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Hlavní autoři:	Weining Yan, Zhilong Chu, Kang Qin, Chengyu Cui, Xi Yu, Xinfeng Yan, Chunxia Ma, Shui Sun, Wei Li, Weiqiang Liang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2026-03-01
Edice:	Stem Cell Research & Therapy
Témata:	Osteoarthritis Progenitor-like chondrocytes Single-cell RNA sequencing Cartilage regeneration Cell heterogeneity Pseudotime analysis
On-line přístup:	https://doi.org/10.1186/s13287-026-04969-8
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