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Delayed Spine Pruning of Direct Pathway Spiny Projection Neurons in a Mouse Model of Parkinson’s Disease

In animal models of Parkinson’s disease (PD), principal striatal spiny projection neurons (SPNs) lose axospinous synapses. However, there has been a disagreement about whether this loss is restricted to a specific type of SPN or not, as some studies have reported pruning in both direct pathway SPNs...

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Bibliografiska uppgifter
Huvudupphov: Steven M. Graves, D. James Surmeier
Materialtyp: Artigo
Språk:Inglês
Utgiven: Frontiers Media S.A. 2019-02-01
Serie:Frontiers in Cellular Neuroscience
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Länkar:https://www.frontiersin.org/article/10.3389/fncel.2019.00032/full
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