Overcoming NK cell resistance in triple-negative breast cancer via adcc with a humanized anti-CD147 antibody

Abstract Triple-negative breast cancer (TNBC) is an aggressive and clinically challenging subtype defined by the absence of estrogen receptor, progesterone receptor, and HER2 amplification, resulting in poor prognosis and limited therapeutic options. Targeting alternative molecular pathways is urgen...

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Hlavní autoři:	Thanathat Pamonsupornwichit, Kanyarat Thongheang, Nuchjira Takheaw, Kanokporn Sornsuwan, Zaw Ye Htet, On-anong Juntit, Phatcharida Jantaree, Chatchai Tayapiwatana
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Springer 2025-10-01
Edice:	Cancer Immunology, Immunotherapy
Témata:	Breast cancer TNBC CD147 Humanized antibody ADCC NK cell
On-line přístup:	https://doi.org/10.1007/s00262-025-04203-z
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