The Impact of Electrophysiological Diversity on Pattern Completion in Lithium Nonresponsive Bipolar Disorder: A Computational Modeling Approach

ABSTRACT Introduction Patients with bipolar disorder (BD) demonstrate episodic memory deficits, which may be hippocampal‐dependent and may be attenuated in lithium responders. Induced pluripotent stem cell–derived CA3 pyramidal cell–like neurons show significant hyperexcitability in lithium‐responsi...

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Hauptverfasser:	Abraham Nunes, Selena Singh, Anouar Khayachi, Shani Stern, Thomas Trappenberg, Martin Alda
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Wiley 2025-01-01
Schriftenreihe:	Brain and Behavior
Schlagworte:	bipolar disorder CA3 computational modeling lithium
Online-Zugang:	https://doi.org/10.1002/brb3.70209
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