Preexisting cell state rather than stochastic noise confers high or low infection susceptibility of human lung epithelial cells to adenovirus

ABSTRACT Viruses display large variability across all stages of their life cycle, including entry, gene expression, replication, assembly, and egress. We previously reported that the immediate early adenovirus (AdV) E1A transcripts accumulate in human lung epithelial A549 cancer cells with high vari...

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Detalhes bibliográficos

Principais autores:	Anthony Petkidis, Maarit Suomalainen, Vardan Andriasyan, Abhyudai Singh, Urs F. Greber
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology 2024-10-01
coleção:	mSphere
Assuntos:	adenovirus infection viral gene expression cell state infection variability infection heterogeneity noise
Acesso em linha:	https://journals.asm.org/doi/10.1128/msphere.00454-24
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