CDKL5 deficiency results in atypical subregion-specific expression of perineuronal nets during mouse visual critical period

Perineuronal nets (PNNs) in the primary visual cortex (V1) are specialized extracellular matrix structures that form predominantly on parvalbumin+ GABAergic neurons, marking the closure of visual critical period plasticity. More recently, PNNs are used to characterize deficits in critical period pla...

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Autori principali:	Brett Addison Emery, Matthew Everett, Logan Reid Dunn, Billy You Bun Lau, Keerthi Krishnan
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2026-05-01
Serie:	Frontiers in Neuroscience
Soggetti:	CDKL5 null male mice PNNs expression rostral V1 V1b V1M visual cortex development
Accesso online:	https://www.frontiersin.org/articles/10.3389/fnins.2026.1769195/full
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