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Exploration of multifaceted molecular mechanism of angiotensin-converting enzyme 2 (ACE2) in pathogenesis of various diseases

Angiotensin converting enzyme 2 (ACE2) is a homolog of ACE (a transmembrane bound dipeptidyl peptidase enzyme). ACE2 converts angiotensinogen to the heptapeptide angiotensin-(1–7). ACE2 and its product, angiotensin-(1–7), have counteracting effects against the adverse actions of other members of ren...

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Principais autores: Aditi D. Kunvariya, Shivani A. Dave, Zeal J. Modi, Paresh K. Patel, Sneha R. Sagar
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2023-05-01
Serier:Heliyon
Fag:
Angiotensin-converting enzyme 2
Angiotensin II
Renin-angiotensin system
SARS-CoV-2
Cancer
Neurodegenerative diseases
Online adgang:http://www.sciencedirect.com/science/article/pii/S2405844023028517
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