Destabilization of Heterologous Proteins Mediated by the GSK3β Phosphorylation Domain of the β-Catenin Protein

Background and Aims: Wnt/β-catenin signaling plays important roles in development and cellular processes. The hallmark of canonical Wnt signaling activation is the stabilization of β-catenin protein in cytoplasm and/or nucleus. The stability of β-catenin is the key to its biological functions and is...

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Autori principali:	Yuhan Kong, Hongyu Zhang, Xian Chen, Wenwen Zhang, Chen Zhao, Ning Wang, Ningning Wu, Yunfeng He, Guoxin Nan, Hongmei Zhang, Sheng Wen, Fang Deng, Zhan Liao, Di Wu, Junhui Zhang, Xinyue Qin, Rex C. Haydon, Hue H. Luu, Tong-Chuan He, Lan Zhou
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Cell Physiol Biochem Press GmbH & Co KG 2013-11-01
Serie:	Cellular Physiology and Biochemistry
Soggetti:	β-catenin Wnt signal Protein degradation Green fluorescent protein Destabilized GFP Chimeric proteins Human cancer
Accesso online:	http://www.karger.com/Article/FullText/354518
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