Hexavalent chromium induced metabolic reprogramming, carcinogenesis and tumor progression through PDK1 upregulation

Lung cancer is the leading factor of cancer-related death in the worldwide. Hexavalent chromium [Cr(VI)] is a potential carcinogen for inducing lung cancers. To understand new mechanism of Cr(VI)-induced tumorigenesis and cancer development, we identified that PDK1 expression levels were greatly inc...

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Principais autores:	Wen-Jing Liu, Lin Wang, Fan-Li Sun, Feng-Mei Zhou, Rui-Ke Zhang, Jie Liu, Min Zhao, Li-Hong Wang, Yan-Ru Qin, Yan-Qiu Zhao, Jian-Ge Qiu, Bing-Hua Jiang
Format:	Artigo
Jezik:	Inglês
Izdano:	Elsevier 2024-12-01
Serija:	Ecotoxicology and Environmental Safety
Teme:	Hexavalent chromium PDK1 MiR-493 HIF-1α Carcinogenesis, lung cancer development
Online dostop:	http://www.sciencedirect.com/science/article/pii/S0147651324014179
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