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Lack of immunogenicity for an influenza‐derived peptide across the HLA‐B44 supertype molecules

Abstract Objectives CD8+ T cells are protective against influenza and there is an interest in designing a future CD8+ T‐cell‐mediated vaccine. However, a significant challenge is the extensive polymorphism of Human Leukocyte Antigen class I (HLA‐I) molecules, the targets of CD8+ T cells. Despite thi...

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Autori principali: Samuel Liwei Leong, Janesha C Maddumage, Stephanie Gras, Emma J Grant
Natura: Artigo
Lingua:Inglês
Pubblicazione: Wiley 2025-01-01
Serie:Clinical & Translational Immunology
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Accesso online:https://doi.org/10.1002/cti2.70051
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