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The Chemokine (C-C Motif) Receptor 2 Antagonist INCB3284 Reduces Fluid Requirements and Protects From Hemodynamic Decompensation During Resuscitation From Hemorrhagic Shock

OBJECTIVES:. Clinical correlations suggest that systemic chemokine (C-C motif) ligand (CCL) 2 release may contribute to blood pressure regulation and the development of hemodynamic instability during the early inflammatory response to traumatic-hemorrhagic shock. Thus, we investigated whether blocka...

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Principais autores: Anthony J. DeSantis, MD, McWayne Weche, MD, Garrett A. Enten, MS, Xianlong Gao, MD, PhD, Matthias Majetschak, MD, PhD
Format: Artigo
Sprog:Inglês
Udgivet: Wolters Kluwer 2022-05-01
Serier:Critical Care Explorations
Online adgang:http://journals.lww.com/10.1097/CCE.0000000000000701
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