Incomplete Decarboxylation of Acidic Cannabinoids in GC-MS Leads to Underestimation of the Total Cannabinoid Content in Cannabis Oils Without Derivatization

<b>Background</b>: Cannabis oil titration consists of quantification of the acidic precursors tetrahydrocannabinolic acid (THCA) and cannabidiolic acid (CBDA) and their decarboxylated products, the active neutral cannabinoids delta-9-tetrahydrocannabinol (Δ9-THC) and cannabidiol (CBD), and is recomm...

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Autors principals:	Martina Franzin, Rebecca Di Lenardo, Rachele Ruoso, Riccardo Addobbati
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2025-03-01
Col·lecció:	Pharmaceutics
Matèries:	cannabis oil cannabinoids decarboxylation acid forms GC-MS LC-MS
Accés en línia:	https://www.mdpi.com/1999-4923/17/3/334
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