ATP-dependent transporters: emerging players at the crossroads of immunity and metabolism

Nearly 50 ATP-binding cassette (ABC) transporters are encoded by mammalian genomes. These transporters are characterized by conserved nucleotide-binding and hydrolysis (i.e., ATPase) domains, and power directional transport of diverse substrate classes – ions, small molecule metabolites, xenobiotics...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Akshaya Balasubramanian, Mark S. Sundrud
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Frontiers Media S.A. 2023-10-01
Цуврал:	Frontiers in Immunology
Нөхцлүүд:	ABC transporters MDR1 P-glycoprotein metabolism reactive oxygen species TCR signaling
Онлайн хандалт:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1286696/full
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!