Protein kinase G inhibition preserves photoreceptor viability and function in a new mouse model for autosomal dominant retinitis pigmentosa
Abstract Retinitis Pigmentosa (RP) is the most common inherited retinal degeneration, characterized by an initial loss of rod photoreceptor cells. Photoreceptor cell death has been associated with high levels of cyclic guanosine-3′, 5′- monophosphate (cGMP) in animal models of autosomal recessive RP...
محفوظ في:
| المؤلفون الرئيسيون: | , , , , , , |
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| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
Nature Publishing Group
2025-07-01
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| سلاسل: | Cell Death and Disease |
| الوصول للمادة أونلاين: | https://doi.org/10.1038/s41419-025-07901-9 |
| الوسوم: |
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