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Efficacy of Contractility Modulation Therapy in Patients with Transthyretin Amyloid Cardiomyopathy, Mildly Reduced to Reduced EF and NYHA III and IV: A Multicentric, Prospective Pilot Study for AMY-CCM Registry

Background: Transthyretin cardiac amyloidosis (ATTR-CM) is an infiltrative cardiomyopathy that frequently progresses to symptomatic heart failure (HF), often with mildly reduced or reduced ejection fraction (EF). Standard therapies are limited in NYHA III–IV, and Tafamidis is approved only for the e...

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Principais autores: Procolo Marchese, Francesca Gennaro, Giovanni Mazzotta, Pierfrancesco Grossi, Luigi Cocchiara, Stefano Guarracini, Lorenzo Mazzocchetti, Matteo Ziacchi, Mauro Biffi, Roberta Magnano, Massimo Di Marco, Matteo Ruzzolini, Antonio Bisignani, Matteo Bianco, Paolo Garrone, Walter Grosso Marra, Margherita Cannillo, Carlo Lavalle, Daniele Masarone, Cristina Chimenti
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2025-09-01
Serier:Journal of Cardiovascular Development and Disease
Fag:
amyloidosis
cardiac contractility modulation
heart failure
Online adgang:https://www.mdpi.com/2308-3425/12/10/380
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