FAK auto-phosphorylation site tyrosine 397 is required for development but dispensable for normal skin homeostasis.

Focal adhesion kinase (FAK) is an intensely studied non-receptor tyrosine kinase with roles in cancer and other common human diseases. Despite the large interest in FAK, the in vivo contribution of FAK auto-phosphorylation site tyrosine (Y) 397 to FAK function is incompletely understood. To study FA...

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Автори:	Joel B Heim, Cera A McDonald, Saranya P Wyles, Sindhuja Sominidi-Damodaran, Edwin J Squirewell, Ming Li, Catherine Motsonelidze, Ralph T Böttcher, Jan van Deursen, Alexander Meves
Формат:	Artigo
Мова:	Inglês
Опубліковано:	Public Library of Science (PLoS) 2018-01-01
Серія:	PLoS ONE
Онлайн доступ:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0200558&type=printable
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