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Identification of mechanisms involved in the relaxation of rabbit cavernous smooth muscle by a new nitric oxide donor ruthenium compound

PURPOSE: The aim of this study was to evaluate the relaxation in vitro of cavernous smooth muscle induced by a new NO donor of the complex nitrosil-ruthenium, named trans-[Ru(NH3)4(caffeine)(NO)]C13 (Rut-Caf) and sodium nitroprusside (SNP). MATERIALS AND METHODS: The tissues, immersed in iso...

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Autori principali: João Batista Gadelha de Cerqueira, Lúcio Flávio Gonzaga-Silva, Francisco Ordelei Nascimento da Silva, João Victor Medeiros de Cerqueira, Ricardo Reges Maia Oliveira, Maria Elisabete Amaral de Moraes, Nilberto Robson Falcão do Nascimento
Natura: Artigo
Lingua:Inglês
Pubblicazione: Sociedade Brasileira de Urologia 2012-10-01
Serie:International Brazilian Journal of Urology
Soggetti:
Nitric oxide
Nitrosyl-ruthenium complex
Endothelium, Vascular
Potassium Channel
Accesso online:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382012000500015
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