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3D QSAR Studies of DAMNI Analogs as Possible Non-nucleoside Reverse Transcriptase Inhibitors

The non-nucleoside inhibitors of HIV-1-reverse transcriptase (NNRTIs) are an important class of drugs employed in antiviral therapy. Recently, a novel family of NNRTIs commonly referred to as 1-[2-diarylmethoxy] ethyl) 2-methyl-5-nitroimidazoles (DAMNI) derivatives have been discovered. The 3D-QSAR...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: S. Ganguly, V. Gopalakrishnan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Wiley 2008-01-01
Schriftenreihe:E-Journal of Chemistry
Online-Zugang:http://dx.doi.org/10.1155/2008/712930
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