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Combining a CDK4/6 Inhibitor With Pemetrexed Inhibits Cell Proliferation and Metastasis in Human Lung Adenocarcinoma

BackgroundRecent clinical trials of cyclin-dependent kinase 4/6 inhibitors (CDK4/6i) in human lung adenocarcinoma (LUAD) have not achieved satisfactory results. The disappointing results of single-drug treatments have prompted studies about synergistic therapies of CDK4/6i with other drugs. We aimed...

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Principais autores: Yuan Ke, Cheng-Gong Liao, Zheng-Qing Zhao, Xiao-Min Li, Rong-Jie Lin, Long Yang, He-Long Zhang, Ling-Min Kong
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-05-01
Colecção:Frontiers in Oncology
Assuntos:
CDK4/6 inhibitor
pemetrexed
cell cycle
synergy
lung adenocarcinoma
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fonc.2022.880153/full
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