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In Vivo Antiviral Activity of Baloxavir against PA/I38T-Substituted Influenza A Viruses at Clinically Relevant Doses

Although the prevalence of polymerase acidic (PA)/I38T strains of influenza virus with reduced susceptibility to baloxavir acid is low, there is a possibility of emergence under selective pressure. Furthermore, the virus may be transmitted between humans. We investigated the in vivo efficacy of balo...

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Principais autores: Takayuki Kuroda, Keita Fukao, Shinpei Yoshida, Ryoko Oka, Kaoru Baba, Yoshinori Ando, Keiichi Taniguchi, Takeshi Noshi, Takao Shishido
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2023-05-01
Serier:Viruses
Fag:
baloxavir
oseltamivir
influenza
PA/I38T
antiviral drugs
Online adgang:https://www.mdpi.com/1999-4915/15/5/1154
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