The matricellular receptor LRP1 forms an interface for signaling and endocytosis in modulation of the extracellular tumor environment

The membrane protein low-density lipoprotein receptor related-protein 1 (LRP1) has been attributed a role in cancer. However, its presumably often indirect involvement is far from understood. LRP1 has both endocytic and signaling activities. As a matricellular receptor it is involved in regulation,...

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Principais autores:	Bart eVan Gool, Stéphane eDedieu, Hervé eEmonard, Anton eRoebroek
Formato:	Artigo
Idioma:	Inglês
Publicado:	Frontiers Media S.A. 2015-11-01
Series:	Frontiers in Pharmacology
Assuntos:	Endocytosis Extracellular Matrix Cancer signaling metastasis LRP1
Acceso en liña:	http://journal.frontiersin.org/Journal/10.3389/fphar.2015.00271/full
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