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Genetic features and therapeutic relevance of emergent circulating tumor DNA alterations in refractory non-colorectal gastrointestinal cancers

Abstract Acquired resistance to systemic treatments is inevitable in most cancers, but the genetic basis for this in many cancer types has remained elusive due to constraints in obtaining tissue specimens longitudinally. In the management of gastrointestinal cancers, molecular profiling is conventio...

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Bibliografiske detaljer
Principais autores: David Hsiehchen, Leslie Bucheit, Dong Yang, Muhammad Shaalan Beg, Mir Lim, Sunyoung S. Lee, Pashtoon Murtaza Kasi, Ahmed O. Kaseb, Hao Zhu
Format: Artigo
Sprog:Inglês
Udgivet: Nature Portfolio 2022-12-01
Serier:Nature Communications
Online adgang:https://doi.org/10.1038/s41467-022-35144-1
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